Phytopharmacology Research Journal http://ojs.prjn.org/index.php/prjn <p><strong>Welcome to </strong><strong>Phytopharmacology Research Journal (PRJ)</strong></p> <p>Phytopharmacology Research Journal (PRJ) is an international open-access peer-review journal committed to publishing review articles, editorial letters, full-length research papers, short communications, and mini-reviews thrice a year.</p> <p><strong>Article processing changes</strong></p> <p>Phytopharmacology Research Journal (PRJ), is an international open-access peer-review journal committed to publishing high quality articles which provide free access to readers. In order to cover the charges of editing, typesetting, formatting, review process, management of journal, and an article processing charge (APC) 300 dollars applies to MS consider for publication.</p> <p><strong>Publishing address</strong></p> <p>Phytopharmacology Research Journal (PRJ), a publication office of Advance Research and Education Center (SMC-PRIVATE) Limited, Rashid Abad, Madina Colony, Street # 7, Office No. 1 Near Dispensary Canal Road, Peshawar, KP, Pakistan. is an international open-access peer-review journal committed to publishing review articles, editorial letters, full-length research papers, short communications, and mini-reviews thrice a year. </p> ADVANCE RESEARCH AND EDUCATION CENTER (SMC-PRIVATE) LIMITED en-US Phytopharmacology Research Journal Qualitative Phytochemical Screening of Buddleja crispa (roots and stem) http://ojs.prjn.org/index.php/prjn/article/view/50 <p>The aim of this study was extraction and Phytochemical Investigation from the Stems and Roots of <em>Buddleja crispa</em>. This plant, belongs to the genus <em>Buddleja </em>and <em>Buddleiaceae </em>family, is a multi-branched shrub or occasionally small tree. This study encounters the phytochemical analysis of <em>Buddleja crispa </em>(roots &amp; stems) in ethanol. Primary metabolites like carbohydrate, fixed oils and lipids, reducing sugar, amino acid, hexose sugar and secondary metabolites like as betacyanin, cardic glycoside, flavonides, saponins, tannins,and triterpenoides were found in all Ethanolic extract of <em>Buddleja crispa</em>. For phytochemical investigation, the Stems and Roots of the plant were collected from Agra Tehsil Batkhela District Malakand on January 28, 2022. The phytochemical investigation in the EtOH extract of Stems and Roots of <em>Buddleja crispa </em>led to the information that most of the biologically active constituents are present except Cyanogenic Glycoside.</p> Imrad Ali Khan Sunbal Khan Hazrat Bilal Copyright (c) 2024 Phytopharmacology Research Journal 2024-02-23 2024-02-23 3 1 1 07 Pharmacological investigations of Ficus carica Linn (Moraceae) http://ojs.prjn.org/index.php/prjn/article/view/53 <p>An endocrine system metabolic disease is diabetes mellitus. Patients with diabetes have excessive blood sugar, which is detrimental to numerous bodily functions because they are either unable to generate insulin or are unable to use it correctly in the body. Elevated blood glucose levels can cause substantial harm over time to the heart, kidneys, eyes, nerves, and blood vessels. Inflammation is a primary protective response, it initiates when the body faces distressed physiological saturations such as swelling, heat, redness, pain, and injury. To repair tissues and destroy or inactivate the attacking organisms’ body inflames. It is a critical reaction originated by the immune systems of the body to suppress inflammation. Natural substances are way better than pharmaceutical drugs as they have many side effects along with curative properties. Various parts of plant and herbal products are utilized traditionally for curing various diseases. The purpose of this study was to evaluate the anti-diabetic activity and anti-inflammatory activity of <em>Ficus carica</em> extract, which was checked by performing anti-diabetic assay Glucose uptake by yeast cells assay (50% at 80µg/ml) and its anti-inflammatory properties by membrane stabilizing assay of red blood cells (74.77 % at 100µg/ml). Both anti-diabetic and anti-inflammatory assays have revealed noteworthy results that give support to the traditional use of <em>Ficus carica</em> as a natural remedy. However, for its further therapeutic effect against diabetes mellitus and Inflammation in vivo study is needed.</p> Muhammad Ibrahim Amir Alam Copyright (c) 2024 Phytopharmacology Research Journal 2024-02-23 2024-02-23 3 1 8 12 Phytochemical and Biological Studies of Cucurbitaceae: A Mini- Review http://ojs.prjn.org/index.php/prjn/article/view/62 <p>Cucubitaceae is the largest family of fruits and vegetables consisting of more than 800 species; with characteristic edible and medicinal value. This family serves as a reservoir for numerous phytochemicals, including tannins, cardiac glycosides, terpenoides, carbohydrates, resins, saponins, carotenoids, and phytosterols. These phytochemicals impart distinguished anti-microbial, anti-oxidant, anti-viral, anti-ulcerative, hepatoprotective, cardio-porotective, anti-cancer and anti-diabetic properties. These traits attribute to its distinctive biological impetus; as discussed in this min-review.</p> Nabia Hafeez Copyright (c) 2024 Phytopharmacology Research Journal 2024-02-23 2024-02-23 3 1 13 23 Qualitative Phytochemical Analysis of Roots, Stem, and Leaves Extracts of Uritica Dioica http://ojs.prjn.org/index.php/prjn/article/view/63 <p>Plants have found extensive use in both traditional and modern medicinal practices globally. Plant-derived remedies present a secure alternative, characterized by the absence of potential side effects commonly linked to pharmaceutical drugs. The comprehensive phytochemical analysis of medicinal plants has unveiled a diverse range of bioactive compounds within plants traditionally employed for medicinal purposes, thereby highlighting a broad spectrum of therapeutic properties. In the continuous investigation, a meticulous and thorough chemical identification process was undertaken for the Lebanese medicinal plant <em>Urtica dioica</em>. This rigorous approach not only substantiates the traditional applications of nettle but also emphasizes the considerable pharmaceutical value inherent in the plant. This study contributes significantly to our understanding of the plant's chemical composition, reinforcing its potential as a valuable resource in pharmaceutical research. The results obtained not only substantiate the traditional applications of nettle but also underscore the substantial pharmaceutical value inherent in the plant. Furthermore, this study has resulted in the successful isolation and characterization of different compounds from the distilled water, methanol and acetone extract of <em>Urtica dioica</em>. This comprehensive approach significantly contributes to enhancing our understanding of the plant's chemical composition, thereby reinforcing its potential as a valuable resource in pharmaceutical research.</p> Muhammad Niaz Hafsa Abrar Saleha Ashfaq Naqash Khan Noor e Baseerat Ramla Jadoon Ayesha Abrar Copyright (c) 2024 Phytopharmacology Research Journal 2024-02-24 2024-02-24 3 1 24 30 Qualitative Phytochemical Analysis and In Vitro Antibacterial Activity of Punica Granatum http://ojs.prjn.org/index.php/prjn/article/view/64 <p>Plant materials remain an essential tool in the global battle against serious diseases. In underdeveloped nations, conventional medical practices particularly the use of medicinal plants remain essential for meeting basic health needs. Certain bioactive compounds that have different physiological effects on the human body are thought to be responsible for these plants' medicinal value. Notable bioactive components found in plants include tannins, alkaloids, flavonoids, and phenolic compounds. Recent years have seen a marked increase in antibiotic resistance due to the rising incidence of infections, which presents a more difficult therapeutic problem. Higher plant-derived natural products may contain antimicrobial agents with distinct modes of action. Plant-derived compounds have demonstrated efficiency in treating infectious diseases, with minimal side effects frequently associated with alongside. The current investigation aimed to explore the phytochemical profile and in vitro antibacterial efficacy of <em>Punica granatum</em>. Phytochemical analysis revealed the presence of flavonoids, tannins, saponins, quinones, proteins, phenols, alkaloids, and carbohydrates. <em>In vitro</em>, antibacterial assessments were conducted using the agar well diffusion methods. The findings from this study suggest the potential utility of <em>Punica granatum</em> in the treatment of diseases caused by the tested organisms.</p> <p><strong> </strong></p> Muhammad Niaz Hafsa Abrar Saleha Ashfaq Naqash Khan Muhammad Awais Noor e Baseerat Ramla Jadoon Ayesha Abrar Muhammad Kashif Kareem Ullah Copyright (c) 2024 Phytopharmacology Research Journal 2024-02-24 2024-02-24 3 1 31 38