In vitro antimicrobial activity of Rumex Dentatus L. (Polygonaceae) plant extracts

Abstract

The realization of the treatment lies in the continuous exploration of new drugs to counteract the challenges pretended by the resilient kinds of different microorganisms. Rumex dentatus L. also entitled toothed dock or dentate dock typically utilized as an antimicrobial agent. Almost 150 different species of the genus Rumex are extensively found all over the world. Conventionally, Rumex dentatus is employed for the cure of countless disorders in the body of organisms. In the current research, we evaluated the phytochemical investigation of the existence of numerous antimicrobial activities of the whole plant extracts of distinct solvents namely ethanol, ethyl acetate, methanol, hexane and water. Rumex dentatus against various microbes such as gram-positive bacteria namely, B. subtilis, S. aureus, B. atrophoeus, gram-negative bacteria such as S. typhi, K. pneumoniae and E. coli and fungal strains including, C. albicans, Aspergillus and Rhizopus by in-vitro agar diffusion technique. The effectiveness order of different solvent extracts was ethanol > ethyl acetate > methanol > hexane > aqueous extract respectively. An Ethanolic extract of the plant under investigation exhibited the maximum inhibitory activity against fungus C. albicans with a zone of inhibition 22 ± 0.23 mm. in case of Gram-positive and Gram-negative bacteria, noteworthy effect was expressed by ethanolic extract against S. aureus with a zone of inhibition 18±0.16 mm and E. coli with a zone of inhibition 19±0.08 mm. The present approach offers a scientific base for the noteworthy practice of this plant in the cure of numerous pathological diseases.