Alginate-Encapsulated Silver Nanoparticles from Plant Extracts: A Biocompatible and Effective Approach for Antibacterial Wound Dressings

Abstract

The shift toward sustainable, plant-derived nanomaterials aligns with global efforts to develop eco-friendly biomedical solutions. By leveraging the synergistic effects of biopolymeric hydrogels and green nanotechnology, alginate-encapsulated plant-mediated AgNPs present a promising alternative to conventional wound dressings, reducing dependency on synthetic antibiotics and mitigating the risk of antimicrobial resistance. Their biocompatibility, antimicrobial potency, and wound-healing benefits highlight their potential as a next-generation wound dressing material. We advocate for increased research, development, and clinical implementation of alginate-based silver nanoparticle hydrogels as a transformative approach in antibacterial wound care. The convergence of biopolymers, nanotechnology, and phytochemistry represents a paradigm shift in advanced wound management, offering effective, safe, and sustainable solutions for infection control and tissue regeneration.